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OCR: release Somatostatin is an inhibitor of hormon nulation ofand blocks the response to hormonal sti e of the effector tissue. It inhibits a wide rang most gastrointestinal functions (Fig. 19.7), the of clinically important being the inhibitior tion, and pancreatic secretions, gallbladder contra asma insulin release. Somatostatin levels in p e marked increase after food ingestion, with a mor with response seen with fat and protein than carbohydrate, although the physiologica importance of this response is unknown See earlier: · Gut Neuropeptides